Initial symptoms can vary, common childhood symptoms are: a swollen abdomen due to an enlarged liver, a history of poor growth or short stature, frequent feeding – always hungry, pisodes of low blood sugar (hypoglycaemia) on fasting, and excessive tiredness following activity.
However, with good dietary management, people wih GSD6 can lead a normal life, can have unaffected children and should live into old age.
Potential complications in later life can include cirrhosis (scarring) and/or adenomas on the liver. Pregnancy should be closely monitored. Those affected by GSD6 may find their symptoms lessen as they become adults. We generally need less energy as we get older because we are not growing.